ProfDarran O'Connor

Professor

School of Pharmacy and Biomolecular Sciences

  • Professor
    School of Pharmacy and Biomolecular Sciences
  • +353 1 402 2596 (Work)
  • RCSI, Molecular & Cellular Therapeutics, 123 St Stephens Green, Dublin 2

BIOGRAPHY

Prof O’Connor is Head of the School of Postgraduate Studies and a molecular oncologist who obtained his PhD from Trinity College Dublin/RCSI in 2000. Subsequently, he conducted his postdoctoral training in cancer biology at Columbia University, New York and the University of Glasgow under the supervision of Prof Nick La Thangue, FRSE. He also spent addition time as a Visiting Fellow at the Dana-Farber Cancer Institute/Harvard Medical School and the Netherlands Cancer Institute where he joined the group of Prof Rene Bernards. Darran returned to Ireland in 2004 as a HRB Career Development Fellow. In 2009 he was employed as a Research Fellow in Cancer Biology at UCD within the School of Biomolecular and Biomedical Science and appointed as Senior Lecturer in Cancer Biology within SBBS in 2013. He moved his research group to RCSI in August 2015. Darran's team (funded by SFI, The European Commission, The Susan G Komen Foundation, The Irish Cancer Society and The Irish Research Council) has extensive experience in the discovery of molecular determinants of cancer progression (via transcriptomic/functional genomic profiling), functional analysis using in vitro and xenograft models, and their clinical translation utilizing tissue microarrays. He was elected to the council of the Irish Association for Cancer Research in 2011 and awarded the 9th St Luke's Young Investigator award in 2012. Other prestigious awards include fellowships from the European Molecular Biology Organisation and the Human Frontiers Science Programme. Publications: 60 peer reviewed papers to date, including in Nature Cell Biology, Nature Reviews Cancer, Nature Communications, Journal of Clinical Oncology, JNCI, Clinical Cancer Research & Cancer Research among others

ACADEMIC POSITIONS

  • Professor of Molecular Oncology
    Royal College of Surgeons in Ireland, School of Pharmacy & Biomolecular Sciences, Dublin, Ireland1 Oct 2022
  • Associate Professor of Molecular Oncology
    Royal College of Surgeons in Ireland, Molecular & Cellular Therapeutics, Dublin, Ireland1 Oct 2018 - 30 Sep 2022
  • Senior Lecturer (Clinical Pharmacology)
    Royal College of Surgeons in Ireland, Molecular & Cellular Therapeutics, Dublin, Ireland3 Aug 2015 - 30 Sep 2018
  • Senior Lecturer (Pharmacology)
    University College Dublin, School of Biomolecular & Biomedical Science, Dublin, Ireland1 Nov 2013 - 31 Jul 2015

DEGREES

  • PhD (Cancer Biology)
    Trinity College Dublin/RCSI, Dublin, Ireland1 Aug 1995 - 17 Nov 2020
  • MSc (Biological Sciences)
    Dublin City University, Dublin, Ireland1 Sep 1994 - 31 Jul 1995
  • BA (Mod) Microbiology
    Trinity College Dublin, Dublin, Ireland1 Sep 1990 - 1 Jun 1994

POSTGRADUATE TRAINING

  • Postdoctoral Research Associate
    Columbia University, NY, Pathology, New York, United States2 Oct 2000 - 22 Jun 2001
    Cancer BiologyPostdoctoral FellowshipSupervised by Chellappan S
  • Postdoctoral Fellow
    University of Glasgow, Institute of Biological and Life Sciences, Glasgow, Scotland25 Jun 2001 - 9 Dec 2004
    Cancer BiologyPostdoctoral FellowshipSupervised by La Thangue NB
  • Postdoctoral Fellow
    University College Dublin, School of Biomolecular & Biomedical Sciences, Dublin, Ireland10 Dec 2004 - 30 Sep 2006
    Cancer BiologyPostdoctoral FellowshipSupervised by Gallagher WM
  • HRB Postdoctoral Fellow
    University College Dublin, School of Biomolecular & Biomedical Sciences, Dublin, Ireland1 Oct 2006 - 30 Sep 2009
    Cancer BiologyPostdoctoral FellowshipSupervised by Gallagher WM
  • Research Fellow
    University College Dublin, School of Biomolecular & Biomedical Sciences, Dublin, Ireland1 Oct 2009 - 31 Oct 2013
    Cancer BiologyOtherSupervised by Gallagher WM

RESEARCH SUB-AREAS

  • Bioinformatics, Genomics, Genetic Analysis
  • Breast Cancer
  • Colorectal Cancer
  • Diagnostics
  • Drug resistance
  • Genomics
  • Inflammation
  • Metastasis
  • Proteomics
  • Therapeutics

SUSTAINABLE DEVELOPMENT GOALS (UNSDGS)

  • 3 Good Health and Well Being

RESEARCH CLUSTERS