DrChris Greene

Dr Chris Greene is a Star Research Lecturer in the Department of Physiology and Medical Physics and FutureNeuro Research Centre. He graduated from Dublin City University in 2013 with a First-Class Honours degree in Genetics and Cell Biology. He undertook his PhD under the supervision of Professor Matthew Campbell in the Smurfit Institute of Genetics in Trinity College Dublin, graduating in 2018. His thesis explored the regulation of the blood-brain barrier in 22q11.2 deletion syndrome and schizophrenia combining molecular biology, transgenic models and behavioural neuroscience. During his postdoctoral training, he used neuroimaging approaches to identify biomarkers of disease in people with epilepsy, concussion and long Covid. This led to the discovery that blood-brain barrier breakdown occurs during acute Covid infection and persists in people who develop neurological symptoms in long Covid.

In 2024 he was hired as a Star Research Lecturer in the Department of Physiology and Medical Physics and FutureNeuro Research Centre at the Royal College of Surgeons in Ireland. His research is at the intersection of neuroscience, vascular biology, and immunology to understand how the barriers of the central nervous system regulate brain function in health and disease. His group explores the molecular determinants of blood-brain barrier formation and the development of the cerebral vasculature with a particular interest in understanding why certain brain regions are vulnerable to trauma and disease.

He has published numerous research articles focused on understanding the pathophysiology of diseases such as epilepsy, traumatic brain injury, long Covid and chronic traumatic encephalopathy.